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Searching the Cytochrome P450 Enzymes for the Metabolism of Meranzin Hydrate: A Prospective Antidepressant Originating from Chaihu-Shugan-San

Meranzin hydrate (MH), an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), was first isolated in our laboratory and was found to possess anti-depression activity. However, the role of cytochrome P450s (CYPs) in the metabolism of MH was unclear. In this...

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Detalles Bibliográficos
Autores principales: Huang, Xi, Guo, Ying, Huang, Wei-hua, Zhang, Wei, Tan, Zhi-rong, Peng, Jing-bo, Wang, Yi-cheng, Hu, Dong-li, Ouyang, Dong-sheng, Xiao, Jian, Wang, Yang, Luo, Min, Chen, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245237/
https://www.ncbi.nlm.nih.gov/pubmed/25427198
http://dx.doi.org/10.1371/journal.pone.0113819