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Exposure to cigarette smoke impacts myeloid-derived regulatory cell function and exacerbates airway hyper-responsiveness

Cigarette smoking enhances oxidative stress and airway inflammation in asthma, the mechanisms of which are largely unknown. Myeloid-derived regulatory cells (MDRC) are free radical producing immature myeloid cells with immunoregulatory properties which have recently been demonstrated as critical reg...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Jin, Tong Huan, Farhana, Aisha, Freeman, Jason, Estell, Kim, Zmijewski, Jaroslaw, Gaggar, Amit, Thannickal, Victor J, Schwiebert, Lisa M, Steyn, Adrie JC, Deshane, Jessy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245361/
https://www.ncbi.nlm.nih.gov/pubmed/25365203
http://dx.doi.org/10.1038/labinvest.2014.126