Cks Overexpression Enhances Chemotherapeutic Efficacy by Overriding DNA Damage Checkpoints

Cks1 and Cks2 are adaptor-like proteins that bind many cyclin-dependent kinases (Cdks). A wealth of clinical data has shown that Cks proteins are overexpressed in many types of human cancers and this often correlates with increased tumor aggressiveness. Previously, we showed that Cks overexpression...

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Detalles Bibliográficos
Autores principales: del Rincón, Sonia V., Widschwendter, Martin, Sun, Dahui, Ekholm-Reed, Susanna, Tat, John, Teixeira, Leonardo K., Ellederova, Zdenka, Grolieres, Elise, Reed, Steven I., Spruck, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245389/
https://www.ncbi.nlm.nih.gov/pubmed/24858038
http://dx.doi.org/10.1038/onc.2014.137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245389/
https://www.ncbi.nlm.nih.gov/pubmed/24858038
http://dx.doi.org/10.1038/onc.2014.137

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