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Vimentin regulates lung cancer cell adhesion through a VAV2-Rac1 pathway to control focal adhesion kinase activity

Vimentin is an intermediate filament protein whose expression correlates with increased metastatic disease, reduced patient survival, and poor prognosis across multiple tumor types. Despite these well-characterized correlations, the molecular role of vimentin in cancer cell motility remains undefine...

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Detalles Bibliográficos
Autores principales: Havel, Lauren S., Kline, Erik R., Salgueiro, Alessandra M., Marcus, Adam I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245398/
https://www.ncbi.nlm.nih.gov/pubmed/24858039
http://dx.doi.org/10.1038/onc.2014.123