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UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase from the snail Biomphalaria glabrata – substrate specificity and preference of glycosylation sites

O-glycosylation is a widely occurring posttranslational modification of proteins. The glycosylation status of a specific site may influence the location, activity and function of a protein. The initiating enzyme of mucin-type O-glycosylation is UDP-GalNAc:polypeptide GalNAc transferase (ppGalNAcT; E...

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Detalles Bibliográficos
Autores principales: Taus, Christopher, Windwarder, Markus, Altmann, Friedrich, Grabherr, Reingard, Staudacher, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245494/
https://www.ncbi.nlm.nih.gov/pubmed/25338825
http://dx.doi.org/10.1007/s10719-014-9565-3