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Deficits in memory-guided limb movements impair obstacle avoidance locomotion in Alzheimer's disease mouse model

Memory function deficits induced by Alzheimer's disease (AD) are believed to be one of the causes of an increased risk of tripping in patients. Working memory contributes to accurate stepping over obstacles during locomotion, and AD-induced deficits of this memory function may lead to an increa...

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Detalles Bibliográficos
Autores principales: Setogawa, Susumu, Yamaura, Hiroshi, Arasaki, Tomoko, Endo, Shogo, Yanagihara, Dai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245527/
https://www.ncbi.nlm.nih.gov/pubmed/25427820
http://dx.doi.org/10.1038/srep07220