Anthrapyrazolone analogues intercept inflammatory JNK signals to moderate endotoxin induced septic shock

Severe sepsis or septic shock is one of the rising causes for mortality worldwide representing nearly 10% of intensive care unit admissions. Susceptibility to sepsis is identified to be mediated by innate pattern recognition receptors and responsive signaling pathways of the host. The c-Jun N-termin...

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Detalles Bibliográficos
Autores principales: Prasad, Karothu Durga, Trinath, Jamma, Biswas, Ansuman, Sekar, Kanagaraj, Balaji, Kithiganahalli N., Guru Row, Tayur N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245532/
https://www.ncbi.nlm.nih.gov/pubmed/25428720
http://dx.doi.org/10.1038/srep07214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245532/
https://www.ncbi.nlm.nih.gov/pubmed/25428720
http://dx.doi.org/10.1038/srep07214

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