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Anthrapyrazolone analogues intercept inflammatory JNK signals to moderate endotoxin induced septic shock
Severe sepsis or septic shock is one of the rising causes for mortality worldwide representing nearly 10% of intensive care unit admissions. Susceptibility to sepsis is identified to be mediated by innate pattern recognition receptors and responsive signaling pathways of the host. The c-Jun N-termin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245532/ https://www.ncbi.nlm.nih.gov/pubmed/25428720 http://dx.doi.org/10.1038/srep07214 |