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NeatFreq: reference-free data reduction and coverage normalization for De Novo sequence assembly
BACKGROUND: Deep shotgun sequencing on next generation sequencing (NGS) platforms has contributed significant amounts of data to enrich our understanding of genomes, transcriptomes, amplified single-cell genomes, and metagenomes. However, deep coverage variations in short-read data sets and high seq...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245761/ https://www.ncbi.nlm.nih.gov/pubmed/25407910 http://dx.doi.org/10.1186/s12859-014-0357-3 |