Cargando…

NeatFreq: reference-free data reduction and coverage normalization for De Novo sequence assembly

BACKGROUND: Deep shotgun sequencing on next generation sequencing (NGS) platforms has contributed significant amounts of data to enrich our understanding of genomes, transcriptomes, amplified single-cell genomes, and metagenomes. However, deep coverage variations in short-read data sets and high seq...

Descripción completa

Detalles Bibliográficos
Autores principales: McCorrison, Jamison M, Venepally, Pratap, Singh, Indresh, Fouts, Derrick E, Lasken, Roger S, Methé, Barbara A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245761/
https://www.ncbi.nlm.nih.gov/pubmed/25407910
http://dx.doi.org/10.1186/s12859-014-0357-3