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Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush

BACKGROUND: Glaucoma is an optic neuropathy that is characterized by the loss of retinal ganglion cells (RGCs) initiated by damage to axons in the optic nerve. The degeneration and death of RGCs has been thought to occur in two waves. The first is axogenic, caused by direct insult to the axon. The s...

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Detalles Bibliográficos
Autores principales: Mac Nair, Caitlin E, Fernandes, Kimberly A, Schlamp, Cassandra L, Libby, Richard T, Nickells, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245774/
https://www.ncbi.nlm.nih.gov/pubmed/25407441
http://dx.doi.org/10.1186/s12974-014-0194-3