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A Test for Ancient Selective Sweeps and an Application to Candidate Sites in Modern Humans

We introduce a new method to detect ancient selective sweeps centered on a candidate site. We explored different patterns produced by sweeps around a fixed beneficial mutation, and found that a particularly informative statistic measures the consistency between majority haplotypes near the mutation...

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Detalles Bibliográficos
Autores principales: Racimo, Fernando, Kuhlwilm, Martin, Slatkin, Montgomery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245817/
https://www.ncbi.nlm.nih.gov/pubmed/25172957
http://dx.doi.org/10.1093/molbev/msu255