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A Test for Ancient Selective Sweeps and an Application to Candidate Sites in Modern Humans
We introduce a new method to detect ancient selective sweeps centered on a candidate site. We explored different patterns produced by sweeps around a fixed beneficial mutation, and found that a particularly informative statistic measures the consistency between majority haplotypes near the mutation...
Autores principales: | Racimo, Fernando, Kuhlwilm, Martin, Slatkin, Montgomery |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245817/ https://www.ncbi.nlm.nih.gov/pubmed/25172957 http://dx.doi.org/10.1093/molbev/msu255 |
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