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Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice

BACKGROUND: Liver X receptor (LXR) plays a critical regulatory role in metabolism and inflammation, and has been demonstrated to be involved in cardiovascular physiology/pathology. In the present study, we investigated the effect of GW3965, a potent LXR agonist, on diabetic cardiomyopathy (DCM) in t...

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Detalles Bibliográficos
Autores principales: He, Qing, Pu, Jun, Yuan, Ancai, Yao, Tianbao, Ying, Xiaoying, Zhao, Yichao, Xu, Longwei, Tong, Huan, He, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245833/
https://www.ncbi.nlm.nih.gov/pubmed/25416469
http://dx.doi.org/10.1186/s12933-014-0149-0