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Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice
BACKGROUND: Liver X receptor (LXR) plays a critical regulatory role in metabolism and inflammation, and has been demonstrated to be involved in cardiovascular physiology/pathology. In the present study, we investigated the effect of GW3965, a potent LXR agonist, on diabetic cardiomyopathy (DCM) in t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245833/ https://www.ncbi.nlm.nih.gov/pubmed/25416469 http://dx.doi.org/10.1186/s12933-014-0149-0 |