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Improving the safety of cell therapy products by suicide gene transfer

Adoptive T-cell therapy can involve donor lymphocyte infusion after allogeneic hematopoietic stem cell transplantation, the administration of tumor infiltrating lymphocyte expanded ex-vivo, or more recently the use of T cell receptor or chimeric antigen receptor redirected T cells. However, cellular...

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Detalles Bibliográficos
Autores principales: Jones, Benjamin S., Lamb, Lawrence S., Goldman, Frederick, Di Stasi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245885/
https://www.ncbi.nlm.nih.gov/pubmed/25505885
http://dx.doi.org/10.3389/fphar.2014.00254