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Inducible forebrain-specific ablation of the transcription factor Creb during adulthood induces anxiety but no spatial/contextual learning deficits

The cyclic AMP (cAMP)-response element binding protein (CREB) is an activity-dependent transcription factor playing a role in synaptic plasticity, learning and memory, and emotional behavior. However, the impact of Creb ablation on rodent behavior is vague as e.g., memory performance of different Cr...

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Detalles Bibliográficos
Autores principales: Vogt, Miriam A., Inta, Dragos, Luoni, Alessia, Elkin, Hasan, Pfeiffer, Natascha, Riva, Marco A., Gass, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245921/
https://www.ncbi.nlm.nih.gov/pubmed/25505876
http://dx.doi.org/10.3389/fnbeh.2014.00407