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Human Leukocyte Antigen Typing Using a Knowledge Base Coupled with a High-Throughput Oligonucleotide Probe Array Analysis

Human leukocyte antigens (HLA) are important biomarkers because multiple diseases, drug toxicity, and vaccine responses reveal strong HLA associations. Current clinical HLA typing is an elimination process requiring serial testing. We present an alternative in situ synthesized DNA-based microarray m...

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Detalles Bibliográficos
Autores principales: Zhang, Guang Lan, Keskin, Derin B., Lin, Hsin-Nan, Lin, Hong Huang, DeLuca, David S., Leppanen, Scott, Milford, Edgar L., Reinherz, Ellis L., Brusic, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245923/
https://www.ncbi.nlm.nih.gov/pubmed/25505899
http://dx.doi.org/10.3389/fimmu.2014.00597