Timely binding of IHF and Fis to DARS2 regulates ATP–DnaA production and replication initiation

In Escherichia coli, the ATP-bound form of DnaA (ATP–DnaA) promotes replication initiation. During replication, the bound ATP is hydrolyzed to ADP to yield the ADP-bound form (ADP–DnaA), which is inactive for initiation. The chromosomal site DARS2 facilitates the regeneration of ATP–DnaA by catalyzi...

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Detalles Bibliográficos
Autores principales: Kasho, Kazutoshi, Fujimitsu, Kazuyuki, Matoba, Toshihiro, Oshima, Taku, Katayama, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245941/
https://www.ncbi.nlm.nih.gov/pubmed/25378325
http://dx.doi.org/10.1093/nar/gku1051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245941/
https://www.ncbi.nlm.nih.gov/pubmed/25378325
http://dx.doi.org/10.1093/nar/gku1051

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