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Integrated mechanism for the generation of the 5′ junctions of LINE inserts

To elucidate the molecular mechanism of the integration of long interspersed elements (LINEs), we characterized the 5′ ends of more than 200 LINE de novo retrotransposition events into chicken DT40 or human HeLa cells. Human L1 inserts produced 15-bp target-site duplications (TSDs) and zebrafish ZfL...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Katsumi, Kajikawa, Masaki, Okada, Norihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245944/
https://www.ncbi.nlm.nih.gov/pubmed/25378331
http://dx.doi.org/10.1093/nar/gku1067