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ArfA recognizes the lack of mRNA in the mRNA channel after RF2 binding for ribosome rescue
Although trans-translation mediated by tmRNA-SmpB has long been known as the sole system to relieve bacterial stalled ribosomes, ArfA has recently been identified as an alternative factor for ribosome rescue in Escherichia coli. This process requires hydrolysis of nascent peptidyl-tRNA by RF2, which...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245945/ https://www.ncbi.nlm.nih.gov/pubmed/25355516 http://dx.doi.org/10.1093/nar/gku1069 |