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ArfA recognizes the lack of mRNA in the mRNA channel after RF2 binding for ribosome rescue

Although trans-translation mediated by tmRNA-SmpB has long been known as the sole system to relieve bacterial stalled ribosomes, ArfA has recently been identified as an alternative factor for ribosome rescue in Escherichia coli. This process requires hydrolysis of nascent peptidyl-tRNA by RF2, which...

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Detalles Bibliográficos
Autores principales: Kurita, Daisuke, Chadani, Yuhei, Muto, Akira, Abo, Tatsuhiko, Himeno, Hyouta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245945/
https://www.ncbi.nlm.nih.gov/pubmed/25355516
http://dx.doi.org/10.1093/nar/gku1069