The role of G-density in switch region repeats for immunoglobulin class switch recombination

The boundaries of R-loops are well-documented at immunoglobulin heavy chain loci in mammalian B cells. Within primary B cells or B cell lines, the upstream boundaries of R-loops typically begin early in the repetitive portion of the switch regions. Most R-loops terminate within the switch repetitive...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng Z., Pannunzio, Nicholas R., Hsieh, Chih-Lin, Yu, Kefei, Lieber, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245955/
https://www.ncbi.nlm.nih.gov/pubmed/25378327
http://dx.doi.org/10.1093/nar/gku1100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245955/
https://www.ncbi.nlm.nih.gov/pubmed/25378327
http://dx.doi.org/10.1093/nar/gku1100

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