Cargando…

Transcription bypass of DNA lesions enhances cell survival but attenuates transcription coupled DNA repair

Transcription-coupled DNA repair (TCR) is a subpathway of nucleotide excision repair (NER) dedicated to rapid removal of DNA lesions in the transcribed strand of actively transcribed genes. The precise nature of the TCR signal and how the repair machinery gains access to lesions imbedded in stalled...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wentao, Selvam, Kathiresan, Ko, Tengyu, Li, Shisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245964/
https://www.ncbi.nlm.nih.gov/pubmed/25389266
http://dx.doi.org/10.1093/nar/gku1150