SHAPE-Seq 2.0: systematic optimization and extension of high-throughput chemical probing of RNA secondary structure with next generation sequencing

RNA structure is a primary determinant of its function, and methods that merge chemical probing with next generation sequencing have created breakthroughs in the throughput and scale of RNA structure characterization. However, little work has been done to examine the effects of library preparation a...

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Detalles Bibliográficos
Autores principales: Loughrey, David, Watters, Kyle E., Settle, Alexander H., Lucks, Julius B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245970/
https://www.ncbi.nlm.nih.gov/pubmed/25303992
http://dx.doi.org/10.1093/nar/gku909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245970/
https://www.ncbi.nlm.nih.gov/pubmed/25303992
http://dx.doi.org/10.1093/nar/gku909

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