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A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein
[Image: see text] α-Synuclein is an intrinsically disordered protein whose aggregation is implicated in Parkinson’s disease. A second member of the synuclein family, β-synuclein, shares significant sequence similarity with α-synuclein but is much more resistant to aggregation. β-Synuclein is missing...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245978/ https://www.ncbi.nlm.nih.gov/pubmed/25389903 http://dx.doi.org/10.1021/bi5009326 |