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The Specialized Hsp70 (HscA) Interdomain Linker Binds to Its Nucleotide-Binding Domain and Stimulates ATP Hydrolysis in Both cis and trans Configurations

[Image: see text] Proteins from the isc operon of Escherichia coli constitute the machinery used to synthesize iron–sulfur (Fe–S) clusters for delivery to recipient apoproteins. Efficient and rapid [2Fe-2S] cluster transfer from the holo-scaffold protein IscU depends on ATP hydrolysis in the nucleot...

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Detalles Bibliográficos
Autores principales: Alderson, T. Reid, Kim, Jin Hae, Cai, Kai, Frederick, Ronnie O., Tonelli, Marco, Markley, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245983/
https://www.ncbi.nlm.nih.gov/pubmed/25372495
http://dx.doi.org/10.1021/bi5010552