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Resistance Patterns Associated with HCV NS5A Inhibitors Provide Limited Insight into Drug Binding

Direct-acting antivirals (DAAs) have significantly improved the treatment of infection with the hepatitis C virus. A promising class of novel antiviral agents targets the HCV NS5A protein. The high potency and broad genotypic coverage are favorable properties. NS5A inhibitors are currently assessed...

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Detalles Bibliográficos
Autores principales: Issur, Moheshwarnath, Götte, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246218/
https://www.ncbi.nlm.nih.gov/pubmed/25384189
http://dx.doi.org/10.3390/v6114227