Anti-Glycoprotein G Antibodies of Herpes Simplex Virus 2 Contribute to Complete Protection after Vaccination in Mice and Induce Antibody-Dependent Cellular Cytotoxicity and Complement-Mediated Cytolysis

We investigated the role of antibodies against the mature portion of glycoprotein G (mgG-2) of herpes simplex virus 2 (HSV-2) in protective immunity after vaccination. Mice were immunized intramuscularly with mgG-2 and oligodeoxynucleotides containing two CpG motifs plus alum as adjuvant. All C57BL/...

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Detalles Bibliográficos
Autores principales: Görander, Staffan, Ekblad, Maria, Bergström, Tomas, Liljeqvist, Jan-Åke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246227/
https://www.ncbi.nlm.nih.gov/pubmed/25398047
http://dx.doi.org/10.3390/v6114358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246227/
https://www.ncbi.nlm.nih.gov/pubmed/25398047
http://dx.doi.org/10.3390/v6114358

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