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DNA methylation signatures link prenatal famine exposure to growth and metabolism

Periconceptional diet may persistently influence DNA methylation levels with phenotypic consequences. However, a comprehensive assessment of the characteristics of prenatal malnutrition-associated differentially methylated regions (P-DMRs) is lacking in humans. Here we report on a genome-scale analy...

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Detalles Bibliográficos
Autores principales: Tobi, Elmar W., Goeman, Jelle J., Monajemi, Ramin, Gu, Hongcang, Putter, Hein, Zhang, Yanju, Slieker, Roderick C., Stok, Arthur P., Thijssen, Peter E., Müller, Fabian, van Zwet, Erik W., Bock, Christoph, Meissner, Alexander, Lumey, L. H., Eline Slagboom, P., Heijmans, Bastiaan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246417/
https://www.ncbi.nlm.nih.gov/pubmed/25424739
http://dx.doi.org/10.1038/ncomms6592