HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β

Cellular DNA repair processes are crucial to maintain genome stability and integrity. In DNA base excision repair, a tight heterodimer complex formed by DNA polymerase β (Polβ) and XRCC1 is thought to facilitate repair by recruiting Polβ to DNA damage sites. Here we show that disruption of the compl...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Qingming, Inanc, Burcu, Schamus, Sandy, Wang, Xiao-hong, Wei, Leizhen, Brown, Ashley R., Svilar, David, Sugrue, Kelsey F., Goellner, Eva M., Zeng, Xuemei, Yates, Nathan A., Lan, Li, Vens, Conchita, Sobol, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246423/
https://www.ncbi.nlm.nih.gov/pubmed/25423885
http://dx.doi.org/10.1038/ncomms6513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246423/
https://www.ncbi.nlm.nih.gov/pubmed/25423885
http://dx.doi.org/10.1038/ncomms6513

Ejemplares similares