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High-resolution melting analysis reveals low Plasmodium parasitaemia infections among microscopically negative febrile patients in western Kenya

BACKGROUND: Microscopy and rapid diagnostic tests (RDTs) are common tools for diagnosing malaria, but are deficient in detecting low Plasmodium parasitaemia. A novel molecular diagnostic tool (nPCR-HRM) that combines the sensitivity and specificity of nested PCR (nPCR) and direct PCR-high resolution...

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Detalles Bibliográficos
Autores principales: Kipanga, Purity N, Omondi, David, Mireji, Paul O, Sawa, Patrick, Masiga, Daniel K, Villinger, Jandouwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246433/
https://www.ncbi.nlm.nih.gov/pubmed/25399409
http://dx.doi.org/10.1186/1475-2875-13-429