Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites

BACKGROUND: Emerging studies demonstrate that single nucleotide polymorphisms (SNPs) resided in the microRNA recognition element seed sites (MRESSs) in 3′UTR of mRNAs are putative biomarkers for human diseases and cancers. However, exhaustively experimental validation for the causality of MRESS SNPs...

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Detalles Bibliográficos
Autores principales: Wu, Di, Yang, Gang, Zhang, Lifang, Xue, Jiwei, Wen, Zhining, Li, Menglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246476/
https://www.ncbi.nlm.nih.gov/pubmed/25106527
http://dx.doi.org/10.1186/1471-2164-15-669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246476/
https://www.ncbi.nlm.nih.gov/pubmed/25106527
http://dx.doi.org/10.1186/1471-2164-15-669

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