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Soma size and Ca(v)1.3 channel expression in vulnerable and resistant motoneuron populations of the SOD1(G93A) mouse model of ALS

Although the loss of motoneurons is an undisputed feature of amyotrophic lateral sclerosis (ALS) in man and in its animal models (SOD1 mutant mice), how the disease affects the size and excitability of motoneurons prior to their degeneration is not well understood. This study was designed to test th...

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Detalles Bibliográficos
Autores principales: Shoenfeld, Liza, Westenbroek, Ruth E., Fisher, Erika, Quinlan, Katharina A., Tysseling, Vicki M., Powers, Randall K., Heckman, Charles J., Binder, Marc D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246589/
https://www.ncbi.nlm.nih.gov/pubmed/25107988
http://dx.doi.org/10.14814/phy2.12113