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Raf kinase inhibitor protein inhibits cholangiocarcinoma cell metastasis by downregulating matrix metalloproteinase 9 and upregulating tissue inhibitor of metalloproteinase 4 expression

Cholangiocarcinoma cells originate in the biliary epithelium. The cells easily metastasize and cause relapse. The effect of Raf kinase inhibitor protein (RKIP) on the biological behavior of cholangiocarcinoma cells is not yet clear. In the present study, RKIP and cytokeratin 19 expression was detect...

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Detalles Bibliográficos
Autores principales: MA, JUNJI, SHI, JUNLI, ZHAO, DONGQIANG, CHENG, LIJUAN, WANG, WENBIN, LI, FANGFANG, JIANG, XIAOYU, JIANG, HUIQING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246646/
https://www.ncbi.nlm.nih.gov/pubmed/25435928
http://dx.doi.org/10.3892/ol.2014.2637