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Insulin-like growth factor-I induces epithelial to mesenchymal transition via GSK-3β and ZEB2 in the BGC-823 gastric cancer cell line

Metastasis is the most common cause of mortality in patients with gastric cancer. Epithelial-to-mesenchymal transition (EMT), which may be stimulated by insulin-like growth factor-I (IGF-I) is involved in the metastasis of numerous tumors; however, the molecular mechanism by which IGF-I may induce t...

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Detalles Bibliográficos
Autores principales: LI, HEMING, XU, LING, ZHAO, LEI, MA, YANJU, ZHU, ZHITU, LIU, YUNPENG, QU, XIUJUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246767/
https://www.ncbi.nlm.nih.gov/pubmed/25435948
http://dx.doi.org/10.3892/ol.2014.2687