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Even modest prediction accuracy of genomic models can have large clinical utility

Whole Genome Prediction (WGP) jointly fits thousands of SNPs into a regression model to yield estimates for the contribution of markers to the overall variance of a particular trait, and for their associations with that trait. To date, WGP has offered only modest prediction accuracy, but in some cas...

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Detalles Bibliográficos
Autores principales: Dhurandhar, Emily J., Vazquez, Ana I., Argyropoulos, George A., Allison, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246888/
https://www.ncbi.nlm.nih.gov/pubmed/25506355
http://dx.doi.org/10.3389/fgene.2014.00417