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Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer

BACKGROUND: Epoxyeicosatrienoic acids (EETs) are derived from arachidonic acid by cytochrome P450 (CYP) and metabolized by soluble epoxide hydrolase (sEH). EETs have been associated with cardiovascular disease, diabetes and several cancer diseases. However, the distribution in tissue and role of CYP...

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Detalles Bibliográficos
Autores principales: Wei, Xiaolong, Zhang, Donghong, Dou, Xiaowei, Niu, Na, Huang, Wenhe, Bai, Jingwen, Zhang, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247238/
https://www.ncbi.nlm.nih.gov/pubmed/25406731
http://dx.doi.org/10.1186/1471-2407-14-841