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Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer
BACKGROUND: Epoxyeicosatrienoic acids (EETs) are derived from arachidonic acid by cytochrome P450 (CYP) and metabolized by soluble epoxide hydrolase (sEH). EETs have been associated with cardiovascular disease, diabetes and several cancer diseases. However, the distribution in tissue and role of CYP...
Autores principales: | Wei, Xiaolong, Zhang, Donghong, Dou, Xiaowei, Niu, Na, Huang, Wenhe, Bai, Jingwen, Zhang, Guojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247238/ https://www.ncbi.nlm.nih.gov/pubmed/25406731 http://dx.doi.org/10.1186/1471-2407-14-841 |
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