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Clinical significance of epigenetic silencing and re-expression of O6-methylguanine-DNA methyltransferase using epigenetic agents in laryngeal carcinoma

The aim of the present study was to investigate the association between O6-methylguanine-DNA methyltransferase (MGMT) gene expression levels, and DNA methylation status and histone modifications in laryngeal squamous cell carcinoma (LSCC). Chromatin immunoprecipitation, methylation-specific polymera...

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Detalles Bibliográficos
Autores principales: YANG, JING, ZHU, XIN-BING, HE, LI-XIA, GU, ZHAO-WEI, JIN, MING-ZHU, JI, WEN-YUE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247240/
https://www.ncbi.nlm.nih.gov/pubmed/25452816
http://dx.doi.org/10.3892/ol.2014.2662