Cargando…
Clinical significance of epigenetic silencing and re-expression of O6-methylguanine-DNA methyltransferase using epigenetic agents in laryngeal carcinoma
The aim of the present study was to investigate the association between O6-methylguanine-DNA methyltransferase (MGMT) gene expression levels, and DNA methylation status and histone modifications in laryngeal squamous cell carcinoma (LSCC). Chromatin immunoprecipitation, methylation-specific polymera...
Autores principales: | YANG, JING, ZHU, XIN-BING, HE, LI-XIA, GU, ZHAO-WEI, JIN, MING-ZHU, JI, WEN-YUE |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247240/ https://www.ncbi.nlm.nih.gov/pubmed/25452816 http://dx.doi.org/10.3892/ol.2014.2662 |
Ejemplares similares
-
O(6)-methylguanine-DNA methyltransferase in equine sarcoids: molecular and epigenetic analysis
por: Altamura, Gennaro, et al.
Publicado: (2012) -
Induced Synthesis of O(6)‐Methylguanine‐DNA Methyltransferase in Rat Hepatoma Cells Exposed to DNA‐damaging Agents
por: Fukuhara, Masao, et al.
Publicado: (1992) -
O6-methylguanine-DNA methyltransferase activities in biopsies of human melanoma tumours.
por: Egyházi, S., et al.
Publicado: (1995) -
Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells.
por: Kokkinakis, D. M., et al.
Publicado: (1997) -
Regulation of expression of O(6)-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review)
por: CABRINI, GIULIO, et al.
Publicado: (2015)