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Sensing the enemy within: how macrophages detect intracellular Gram-negative bacteria

Caspase-11 contributes to host defense against Gram-negative bacterial pathogens by inducing an inflammatory form of programmed cell death in infected cells. Lipopolysaccharides (LPS) have been identified as the microbial agents that stimulate caspase-11 activation; however, the mechanism of LPS det...

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Detalles Bibliográficos
Autores principales: Demon, Dieter, Vande Walle, Lieselotte, Lamkanfi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Trends Journals 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247376/
https://www.ncbi.nlm.nih.gov/pubmed/25458607
http://dx.doi.org/10.1016/j.tibs.2014.10.006