Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8

BACKGROUND: Calcitonin gene-related peptide-α (CGRPα) is a classic marker of peptidergic nociceptive neurons and is expressed in myelinated and unmyelinated dorsal root ganglia (DRG) neurons. Recently, we found that ablation of Cgrpα-expressing sensory neurons reduced noxious heat sensitivity and en...

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Detalles Bibliográficos
Autores principales: McCoy, Eric S, Zylka, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247560/
https://www.ncbi.nlm.nih.gov/pubmed/25406633
http://dx.doi.org/10.1186/1744-8069-10-69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247560/
https://www.ncbi.nlm.nih.gov/pubmed/25406633
http://dx.doi.org/10.1186/1744-8069-10-69

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