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Reducing bias in open-label trials where blinded outcome assessment is not feasible: strategies from two randomised trials

BACKGROUND: Blinded outcome assessment is recommended in open-label trials to reduce bias, however it is not always feasible. It is therefore important to find other means of reducing bias in these scenarios. METHODS: We describe two randomised trials where blinded outcome assessment was not possibl...

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Detalles Bibliográficos
Autores principales: Kahan, Brennan C, Cro, Suzie, Doré, Caroline J, Bratton, Daniel J, Rehal, Sunita, Maskell, Nick A, Rahman, Najib, Jairath, Vipul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247637/
https://www.ncbi.nlm.nih.gov/pubmed/25416527
http://dx.doi.org/10.1186/1745-6215-15-456