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Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH)

BACKGROUND: Banding-karyotyping and metaphase-directed-fluorescence-in-situhybridization (FISH) may be hampered by low mitotic index in leukemia. Interphase FISH (iFISH) is a way out here, however, testing many probes at the same time is protracted and expensive. Here multiplex-ligation-dependent-pr...

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Detalles Bibliográficos
Autores principales: Alhourani, Eyad, Rincic, Martina, Othman, Moneeb AK, Pohle, Beate, Schlie, Cordula, Glaser, Anita, Liehr, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247644/
https://www.ncbi.nlm.nih.gov/pubmed/25435911
http://dx.doi.org/10.1186/s13039-014-0079-2