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Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer

BACKGROUND: The ErbB family consists of four proteins including (EGFR)/ErbB1, ErbB2, ErbB3, and ErbB4, and plays a crucial role in the promotion of multiple tumorigenic processes. In addition to the traditional pathways of EGFR signaling, EGFR translocates to the nucleus and acts as a transcription...

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Detalles Bibliográficos
Autores principales: Mitsui, Keigo, Yonezawa, Masaoki, Tatsuguchi, Atsushi, Shinji, Seiichi, Gudis, Katya, Tanaka, Shu, Fujimori, Shunji, Sakamoto, Choitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247672/
https://www.ncbi.nlm.nih.gov/pubmed/25416285
http://dx.doi.org/10.1186/1471-2407-14-863