Cargando…

Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration

BACKGROUND: Cigarette smoking is a common and lethal worldwide habit, with considerable mortality stemming from its deleterious effects on heart function. While current theories posit altered blood lipids and fibrinogen metabolism as likely mediators, none have explored the role of the sphingolipid...

Descripción completa

Detalles Bibliográficos
Autores principales: Tippetts, Trevor S, Winden, Duane R, Swensen, Adam C, Nelson, Michael B, Thatcher, Mikayla O, Saito, Rex R, Condie, Tyler B, Simmons, Kurtis J, Judd, Allan M, Reynolds, Paul R, Bikman, Benjamin T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247675/
https://www.ncbi.nlm.nih.gov/pubmed/25416336
http://dx.doi.org/10.1186/1471-2261-14-165