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Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration
BACKGROUND: Cigarette smoking is a common and lethal worldwide habit, with considerable mortality stemming from its deleterious effects on heart function. While current theories posit altered blood lipids and fibrinogen metabolism as likely mediators, none have explored the role of the sphingolipid...
Autores principales: | Tippetts, Trevor S, Winden, Duane R, Swensen, Adam C, Nelson, Michael B, Thatcher, Mikayla O, Saito, Rex R, Condie, Tyler B, Simmons, Kurtis J, Judd, Allan M, Reynolds, Paul R, Bikman, Benjamin T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247675/ https://www.ncbi.nlm.nih.gov/pubmed/25416336 http://dx.doi.org/10.1186/1471-2261-14-165 |
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