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Association of secreted frizzled-related protein 4 (SFRP4) with type 2 diabetes in patients with stable coronary artery disease

BACKGROUND: Secreted frizzled-related proteins (SFRP) are regulators of Wnt-signalling. SFRP4 has been shown to regulate insulin exocytosis and is overexpressed in type 2 diabetes mellitus. Here we characterized the relation of SFRP4 to glucose and triglyceride metabolism and outcomes in patients wi...

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Detalles Bibliográficos
Autores principales: Hoffmann, Michael M, Werner, Christian, Böhm, Michael, Laufs, Ulrich, Winkler, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247677/
https://www.ncbi.nlm.nih.gov/pubmed/25408147
http://dx.doi.org/10.1186/s12933-014-0155-2