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Nucleofection optimization and in vitro anti-tumourigenic effect of TRAIL-expressing human adipose-derived mesenchymal stromal cells

BACKGROUND: Tumour homing capacity of engineered human adipose-derived mesenchymal stromal cells (ADMSCs) expressing anti-tumour agents might be the key for a much safer and yet efficient targeted tumour therapy. However, ADMSCs exhibit resistant to most gene transfection techniques and the use of h...

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Detalles Bibliográficos
Autores principales: Fakiruddin, Kamal Shaik, Baharuddin, Puteri, Lim, Moon Nian, Fakharuzi, Noor Atiqah, Yusof, Nurul Ain Nasim M, Zakaria, Zubaidah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247692/
https://www.ncbi.nlm.nih.gov/pubmed/25469108
http://dx.doi.org/10.1186/s12935-014-0122-8