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Comparison of the efficacy and safety profiles of a pelubiprofen versus celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, phase III, non-inferiority clinical trial

BACKGROUND: Pelubiprofen is a prodrug of 2-arylpropionic acid with relatively selective effects on cyclooxygenase-2 activity. The aim of this study was to compare the efficacy and safety profiles of pelubiprofen with those of celecoxib in patients with rheumatoid arthritis. METHODS: This was a 6-wee...

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Detalles Bibliográficos
Autores principales: Choi, In Ah, Baek, Han-Joo, Cho, Chul-Soo, Lee, Yeon-Ah, Chung, Won Tae, Park, Young Eun, Lee, Yun Jong, Park, Yong-Beom, Lee, Jisoo, Lee, Shin-Seok, Yoo, Wan-Hee, Song, Jung-Soo, Kang, Seong Wook, Kim, Hyun Ah, Song, Yeong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247700/
https://www.ncbi.nlm.nih.gov/pubmed/25403311
http://dx.doi.org/10.1186/1471-2474-15-375