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Arylamine N-acetyltransferase polymorphisms in Han Chinese patients with ankylosing spondylitis and their correlation to the adverse drug reactions to sulfasalazine

BACKGROUND: Polymorphisms of Arylamine N-acetyltransferase (NAT) that contribute to diverse susceptibilities of some autoimmune diseases are also linked to the metabolism of several drugs including sulfasalazine (SSZ). The aim of this study was to investigate the distribution of NAT polymorphisms in...

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Detalles Bibliográficos
Autores principales: Hou, Zhi-duo, Xiao, Zheng-yu, Gong, Yao, Zhang, Yu-ping, Zeng, Qing Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247704/
https://www.ncbi.nlm.nih.gov/pubmed/25413361
http://dx.doi.org/10.1186/2050-6511-15-64