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Simvastatin to modify neutrophil function in older patients with septic pneumonia (SNOOPI): study protocol for a randomised placebo-controlled trial

BACKGROUND: Community-acquired pneumonia (CAP) is considered the leading cause of death from infectious disease in developed countries, while complications of CAP - sepsis being the most common and challenging - increase the risk of mortality. During the progression of sepsis, a state of neutrophil...

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Detalles Bibliográficos
Autores principales: Greenwood, Hannah, Patel, Jaimin, Mahida, Rahul, Wang, Qian, Parekh, Dhruv, Dancer, Rachel CA, Khiroya, Heena, Sapey, Elizabeth, Thickett, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247744/
https://www.ncbi.nlm.nih.gov/pubmed/25146127
http://dx.doi.org/10.1186/1745-6215-15-332